VCE Biology Past Exam Questions

Browse VCE Biology exam questions from 2015–2025, including NHT and VCE papers. Filter by topic, year and paper; open the original source.

Indexed questions and parts1,677in Biology
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Exam years2015–2025Available in this subject

Matching results: 1,677 indexed questions and parts.

Section B, Question 1(a)Question part (a)

Biology2025NHTSingle paper4 marks
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Estimated difficulty · Medium

a. Depending on the food a person eats, E. coli can be exposed to high levels of trp on one day and low levels of trp on another day. Discuss the activity of the repressor protein

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Source: 2025 VCE (NHT) Biology examination (PDF, 10.79 MB)

Section B, Question 1(a)Question part (a)

Biology2025VCESingle paper3 marks
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Report-based difficulty · MediumAverage marks: 67% of available · official reportFull marks: 56% of students · official report

a. Construct a diagram of an mRNA molecule in the space provided below to show the result of mRNA processing of the insulin gene. Label three modifications as a result of mRNA proc

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)

Section B, Question 1(b)Question part (b)

Biology2025VCESingle paper2 marks
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Report-based difficulty · DifficultAverage marks: 39% of available · official reportFull marks: 24% of students · official report

b. Recombinant DNA technologies are used to produce large quantities of human insulin to treat diabetes. Shown below are some of the steps involved in one method used in the produc

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)

Section B, Question 1(b)Question part (b)

Biology2025NHTSingle paper3 marks
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Estimated difficulty · Easy

b. Both humans and E. coli use mRNA and trp in biochemical pathways to produce proteins. Describe the function of both mRNA and frp in the production of proteins. 3 marks o ° =) S

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Source: 2025 VCE (NHT) Biology examination (PDF, 10.79 MB)

Section B, Question 2

Biology2025NHTSingle paper5 marks
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Estimated difficulty · Medium

Question 2 (5 marks) Both human and yeast cells use glucose as an energy source but variations in biochemical pathways produce different products. One variation in a biochemical pa

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Source: 2025 VCE (NHT) Biology examination (PDF, 10.79 MB)

Section B, Question 2

Biology2025VCESingle paper11 marks
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Estimated difficulty · Medium

Question 2 (11 marks) Tryptophan (trp) is one of the least common amino acids in proteins. When needed, some bacteria can synthesise trp. In these bacteria, the trp operon regulate

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Source: 2025 VCE Biology examination (PDF, 2.72 MB)

Section B, Question 2(a)Question part (a)

Biology2025VCESingle paper2 marks
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Report-based difficulty · DifficultAverage marks: 39.5% of available · official reportFull marks: 23% of students · official report

a. Explain how enzymes such as those coded by the genes within the trp operon catalyse biochemical reactions. 2 marks Use the following information to answer part b and part c on p

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)

Section B, Question 2(a)Question part (a)

Biology2025NHTSingle paper2 marks
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Estimated difficulty · Medium

a. Compare the biochemical pathway shown above to fermentation in yeast cells. 2 marks

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Source: 2025 VCE (NHT) Biology examination (PDF, 10.79 MB)

Section B, Question 2(b)Question part (b)

Biology2025NHTSingle paper3 marks
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Estimated difficulty · Easy

b. Coenzymes are used in fermentation. Describe the general role of coenzymes in biochemical pathways. 3 marks Section B

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Source: 2025 VCE (NHT) Biology examination (PDF, 10.79 MB)

Section B, Question 2(b)Question part (b)

Biology2025VCESingle paper5 marks
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Report-based difficulty · MediumAverage marks: 48.6% of available · official reportFull marks: 14% of students · official report

b. Referring to the graph, explain why enzyme activity remains low between 0 and 20 minutes and why it remains steady after approximately 60 minutes. As part of your response, expl

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)

Section B, Question 2(c)Question part (c)

Biology2025VCESingle paper2 marks
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Report-based difficulty · MediumAverage marks: 40% of available · official reportFull marks: 19% of students · official report

c. The model simulation captures the general trend of enzyme activity but does not accurately replicate the experimental data, especially when the bacteria are first moved to a trp

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)

Section B, Question 2(d)Question part (d)

Biology2025VCESingle paper2 marks
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Report-based difficulty · DifficultAverage marks: 24.5% of available · official reportFull marks: 6% of students · official report

d. In the past, bacteria had four stop codons, including UGG, and no codon for trp. The UGG codon in bacteria now codes for trp. Identify a consequence for the bacteria of the UGG

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Source: 2025 VCE Biology examination (PDF, 2.72 MB) · Report: 2025 VCE Biology external assessment report (DOCX, 1.14 MB)
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